Recombinant Human SCN2B, Fc-tagged
产品名称: Recombinant Human SCN2B, Fc-tagged
英文名称: Recombinant Human SCN2B, Fc-tagged
产品编号: SCN2B-8616H
产品价格: 0
产品产地: USA
品牌商标: Creative Biomart
更新时间: null
使用范围: null
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SCN2B is essential for the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which may be associated with either one or more beta-subunits. Alpha-subunits are composed for four homologous domains, each of which contains six transmembrane segments. They are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. SCN2B interacts with TNR and may play a crucial role in clustering and regulation of activity of sodium channels at nodes of ranvier. SCN2B also causes an increase in the plasma membrane surface area and in its folding into microvilli.