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Anti-JNK1 Monoclonal Antibody
产品名称: Anti-JNK1 Monoclonal Antibody
英文名称: Anti-JNK1 Monoclonal Antibody
产品编号: K001441M
产品价格: null
产品产地: 北京
品牌商标: solarbio
更新时间: 2025-02-07T13:54:15
使用范围: WB IF
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-JNK1 Monoclonal Antibody
品牌:solarbio | 货号:K001441M
英文名称 | Anti-JNK1 Monoclonal Antibody |
---|---|
别名 | JNK;JNK-46;JNK1;JNK1A2;JNK21B1/2;PRKM8;SAPK1;SAPK1c |
应用 | WB IF |
稀释比例 | WB 1:1000. IHC 1:100. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 46/54kDa |
Gene ID | 5599 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG2a |
免疫原 | Purified recombinant human JNK1 protein fragments expressed in E.coli. |
性状 | 液体 |
Public Immunogen Range | Purified recombinant human JNK1 protein fragments expressed in E.coli. |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | P45983 |
克隆号 | 1A4-C5-F11 |
克隆类型 | Monoclonal Antibody |
背景资料 | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. |